What if it were possible to go beyond the "self"? To unravel the mysteries of our psyche? Mathilde Ramadier conducted her own experiments with ayahuasca, a drink used for thousands of years by the indigenous peoples of the Amazon, and interviewed 26 "psychonauts." Sometimes more effective than antidepressants in treating depression and addiction, these substances are still classified as narcotics, but in reality offer great hope for the treatment of mental distress.